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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Downregulation of SMIM3 inhibits growth of leukemia via PI3K-AKT signaling pathway and correlates with prognosis of adult acute myeloid leukemia with normal karyotype

Fig. 1

AML samples showed a higher expression of SMIM3 compared to normal samples. A Expression levels of SMIM3 in paired samples of normal and tumor patients in different cancers. B In the TCGA-GTEx database, SMIM3 showed significantly higher expression in AML patients (n = 173) than in normal samples (n = 70). C In the ImmuCo database, the gene expression level of SMIM3 was higher in AML bone marrow mononuclear cells (BMMC, n = 814) than in hematopoietic stem cells (HSC, n = 113). D AML samples (n = 236) from the ZZU cohort showed a significant increase in SMIM3 expression compared to normal bone marrow samples (n = 22). E SMIM3 expression in different cell lines. *, P < 0.05; **, P < 0.01; ***, P < 0.001

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Journal of Translational Medicine

ISSN: 1479-5876

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