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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: circCRKL, a circRNA derived from CRKL, regulates BCR-ABL via sponging miR-877-5p to promote chronic myeloid leukemia cell proliferation

Fig. 2

circCRKL promotes CML cells proliferation in vitro. The efficient and specific knockdown of circCRKL in K562 (A) and K562/G01 (B) cells. C, D CCK-8 assays were used to investigate the effect of circCRKL knockdown on growth in K562 (C) and K562/G01 (D) cells. E, F Effect of circCRKL knockdown on proliferation in K562 and K562/G01 cells was determined by colony formation assays. G, H Flow cytometry was used to analyze the effect of circCRKL suppression on the cell cycle. *p < 0.05, **p < 0.01, and ***p < 0.001

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Journal of Translational Medicine

ISSN: 1479-5876

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