Fig. 1

Effects of sCLU knockdown on malignant behaviors of HCC cells. a sCLU expression in HCCLM3 cells transfected with NC or sh-sCLU was detected by western blotting. b sCLU expression in HCCLM3 cells transfected with NC or sh-sCLU was detected by RT-qPCR. c The migration of HCCLM3 cells was detected by wound-healing assay. d The relative migration distance in C. e The invasion of HCCLM3 cells was detected by transwell assay. f The relative invasive cell number in e. g, h MTT assay was used to detect the viability of HCCLM3 cells transfected with NC or sh-sCLU after sorafenib or doxorubicin treatment. Scale bar, 100 µm. **P < 0.01